Part1. What is Morinda officinalis extract?
Morinda officinalis extract is a plant extract derived from the dried root of Morinda officinalis, a plant of the Rubiaceae family, also known as Jichangfeng, corn vine, and triangular vine. The pure product is brown or off-white powder. It is anthraquinone and flavonoids. For the treatment of impotence and nocturnal emission, cold uterine infertility, irregular menstruation, cold pain in the lower abdomen, rheumatism arthralgia, muscle and bone flaccidity and weakness.
Part2. Purpose
Morinda officinalis extract is often used to enhance the sexual function strength of men and women. It is used for impotence, premature ejaculation, back and knee pain and infertility. It is also used by women to treat infertility and frigidity. In addition, it is also believed to be good for the heart. And like other tonic herbs, it has also been shown to be effective in reducing high blood pressure. Because Morinda officinalis is not only powerful but also extremely well tolerated, it is one of the best tonics. It is considered a major life-prolonging herb and is a common ingredient in Taoist pharmacology.
Part3. Pharmacological effects
1. Enhance the hypothalamus-pituitary-ovary luteinizing function
2. Anti-inflammatory and analgesic
The ethanol extract of Morinda officinalis has certain anti-rheumatoid arthritis effects, and its anti-inflammatory and analgesic effects are closely related to reducing the content of inflammatory mediator PGE2. Morinda officinalis ethanol extract, ethyl acetate fraction, and n-butanol fraction have significant inhibitory effects on the NO content produced by LPS-stimulated RAW264.7 macrophages, indicating that Morinda officinalis may exert anti-inflammatory effects by inhibiting the production of NO .
Morinda officinalis water extract has oil anti-oxidation effect, and the anti-oxidation effect becomes better with the increase of the added amount. Morinda officinalis water extract has better antibacterial effect on bacteria, especially strong antibacterial ability on Staphylococcus aureus, but weak inhibitory effect on yeast and mold. Morinda officinalis n-butanol extract has a protective effect on hypoxia/reoxygenation-injured cardiomyocytes, and its protective effect may be related to the reduction of the contents of TNF-α, IL-1β, and IL-6.
3. Improve thyroid function
Oral administration of Morinda officinalis water decoction can increase the oxygen consumption of mice with hypothyroidism (hypothyroidism modeled by methylthiouracil), and restore the maximum binding capacity of M receptors in the brain of hypothyroid mice to normal. Morinda officinalis nourishing ointment (Morinda officinalis as the main drug) can correct the abnormal increase of cGMP in the blood of rabbits with hypothyroidism and yang deficiency, stabilize the serum T3 level of rabbits, and make the liver, pancreas and spleen of rabbits with hypothyroidism and yang deficiency The structural and morphological abnormalities were alleviated, and the contents of RNA and glycogen in the liver were similar to those of normal control rabbits.
4. Weight gain and anti-fatigue effects
5. Effects on blood system
Some anthraquinone compounds in Morinda officinalis have inhibitory activity on the growth of L1210 leukemia.
6. Immunopromoting effect
Morinda officinalis oligosaccharides can promote cellular immunity.
7. Antidepressant effect
Morinda officinalis water decoction can significantly improve the level of reserpine and its monoamine transmitter in the brain.
8. Corticosterone secretion promoting effect
Clinical studies have shown that Morinda officinalis can reduce the side effects of long-term use of steroids in patients with nephritis and systemic lupus erythematosus, and make it easy to stop taking steroids.
9. Enhance memory
The enhancing effect of Bajisu on long-term potentiation (LTP) of hippocampal synapses may be one of the synaptic mechanisms of promoting learning and memory.
10. Promotes Bone Growth
Both Morinda officinalis water extract and Morinda officinalis polysaccharide can significantly promote the proliferation of osteoblasts cultured in vitro, promote the secretion of alkaline phosphatase and osteocalcin from osteoblasts, and promote the expression of transforming growth factor β1 mRNA in osteoblasts, and Morinda officinalis Tian polysaccharide is superior to Morinda officinalis water extract.
11. Anticancer effect
The anthraquinone components contained in Morinda officinalis have the effect of anti-carcinogenic accelerator, and the crude crystals of its chloroform extract have inhibitory effect on the growth of L1210 leukemia cells.
