Part1：What is Astragaloside IV supplement?
Astragaloside IV is an organic substance with a chemical formula of C41H68O14. It is a white crystalline powder. It is a drug extracted from Astragalus. The main active components in Astragalus are astragalus polysaccharides, astragalus saponins and isoflavones. ), and astragaloside IV was mainly used as the standard for evaluating the quality of astragalus. Pharmacological studies have shown that Astragalus has the functions of enhancing immune function, strengthening the heart and reducing blood pressure, lowering blood sugar, diuresis, anti-aging, and anti-fatigue.
Part2: Physical and chemical properties
【Appearance】: White crystalline powder
【Specification】: more than 98%, detection method HPLC.
【Properties】: Astragalus extract is brown powder.
【Determination of content】: According to high performance liquid chromatography.
Part3: Pharmacological action
The main active ingredients in Astragalus are polysaccharides and astragaloside. Astragaloside is divided into astragaloside I, astragaloside II, and astragaloside IV. Among them, the best biological activity is astragaloside IV, namely astragaloside IV. Astragaloside IV not only has the effect of astragalus polysaccharide, but also has some incomparable effects of astragalus polysaccharide. Its medicinal strength is more than 2 times that of conventional astragalus polysaccharide, and its antiviral effect is 30 times that of astragalus polysaccharide. Because of its low content and good effect, it is also known as "super astragalus polysaccharide".
1. Enhance the body's immunity and improve the body's disease resistance.
It can specifically and non-specifically exclude foreign bodies that invade the body, promote specific, immune and non-specific immunity, and improve the body's disease resistance. It can promote the production of antibodies in the body, and can significantly increase the number of antibody-forming cells and the measured value of hemolysis. Astragaloside IV can significantly improve the level of lymphocyte transformation and the formation rate of E rosettes in coccidioid-immunized chickens, and is an effective activator of the monocyte-macrophage system. Astragaloside IV can also improve oxidation, increase GSH-PX and SOD activities in immune organs, and improve immune defense and immune surveillance functions.
2. Antiviral effect.
Its antiviral principle: stimulate the function of macrophages and T cells, increase the number of cells forming the E ring, induce cytokines, promote the induction of interleukins, and make the animal body produce endogenous interferon, so as to achieve anti-virus the goal of. The test proved that the total protection rate of astragaloside IV on IBD can reach 98.33%, which can effectively prevent and treat IBD, and there is no significant difference compared with the control effect of high immunity egg yolk solution. Astragaloside IV can enhance the function of the antioxidant enzyme system in the body, reduce the content of L0, and reduce the damage of reactive oxygen species to the body, thereby reducing the morbidity and mortality of MD. It can improve the immune function of the body caused by tumors, promote the activation of immune cells to release endogenous factors, and prevent the killing and inhibition of tumor cells caused by peroxidation. Astragaloside IV has the effect of inhibiting the growth of influenza virus and inhibiting the activity of sialidase. , has a significant effect on the function of influenza virus membrane and affects the adsorption and penetration of the virus to sensitive cells. The mortality of poultry and the decline in egg production rate were greatly reduced, and the egg production rate and eggshell quality recovery were significantly better than those of the control group using only amantadine, and the effect of astragalus polysaccharide was not obvious; Strong killing and inhibitory effect. The premise is that astragaloside IV is used before the infection of ND virus is found, so it is best to use astragaloside IV for a long time. Avian myeloblastosis (AMB) 3-day-old AA broilers are infected with AMB virus and given astragaloside IV at the same time. The morbidity and mortality of AMB, increase the LPO content in immune organs such as spleen and thymus, and significantly enhance the clearance of myeloid tumor cells by immune organs such as spleen and thymus; And other respiratory diseases also have obvious preventive and therapeutic effects.
3. Anti-stress effect.
Astragaloside IV can prevent adrenal hyperplasia and thymus atrophy in the alert period of stress response, prevent abnormal changes in stress response resistance period and exhaustion period, and play an anti-stress role, especially for the bidirectional regulation of enzymes in the process of nutrient metabolism. Significantly, the effects of heat stress on the physiological functions of the body were alleviated and eliminated to a certain extent.
4. As a growth promoter.
It can enhance the physiological metabolism of cells, promote blood circulation, enhance the metabolism of animal bodies, and play a role in nutrition and health care. Studies have shown that it can promote the growth of bifidobacteria and lactic acid bacteria, and has the effect of prebiotics.
5. Astragaloside IV can improve cardiopulmonary function.
Strengthen cardiac contractility, protect the myocardium, and resist heart failure. It also has liver protection, anti-inflammatory, analgesic and other effects. It can be used as an adjuvant therapy for various viral and bacterial diseases.
